However, high YY1 expression only correlated with squamous cell carcinoma (SCC) patients, while high expression of ZNF322A, Shh, and CD31 (ZNF322Ahigh/Shhhigh/CD31high) tended to occur more frequently in adenocarcinoma (ADC) patients than in SCC patients (Table 1). The gene discussed is SHH; the disease is squamous cell carcinoma.