We also previously performed a cell-based high throughput screening for the identification of small-molecule pendrin inhibitors; the pendrin inhibitor we screened (YS-01) showed a strongly therapeutic effect in an OVA-induced allergy asthma murine model, where it inhibited pendrin/OSCN-/NF-κB-mediated airway inflammation 20. The gene discussed is SLC26A4; the disease is inflammatory response.