After performing 2D gel electrophoresis of proteins from aortas of Prdx2+/+ and Prdx2−/− mice infused with Ang II, we identified 37 increased spots and 23 decreased spots with differences of at least twofold between the two groups using MALDI-TOF analysis (Supplementary Fig. 4a, b), which revealed that albumin precursor levels were significantly increased in AAA from Prdx2−/− mice infused with Ang II compared with those from controls (Supplementary Table 1). Here, AGT is linked to triple-A syndrome.