In addition, ARID2 expression level was examined in 116 human CSCC tissue microarrays using IHC and found to be significantly lower in advanced-stage (FIGO 2018, stages III and IV, n = 23) CSCC patients than in early-stage CSCC patients (FIGO 2018, stages I and II, n = 93) (Supplementary Fig. S4a). Here, ARID2 is linked to skin squamous cell carcinoma.