WNK2 and cancer: The results summarized in Table 3, revealed many enriched KEGG pathways associated with cancer (p < 0.001 for alcohol and p < 0.01 for nicotine–alcohol), Glutamatergic synapse (p < 0.001 for alcohol and p < 0.01 for nicotine–alcohol), axon guidance (p < 0.01 for alcohol and p < 0.01 for nicotine–alcohol), and Mitogen-Activated Protein Kinase (MAPK) signaling pathway (p < 0.001 for alcohol and p < 0.001 for nicotine–alcohol).