Western blot analysis demonstrated that while the evaluated EGFR-mutated NSCLC cell lines expressed various levels of IGF-1R protein, AXL-low-expressing tumor cells reported higher levels of phosphorylated IGF-1R (pIGF-1R) compared to AXL-high tumor cell lines (Fig. 1b). Here, IGF1R is linked to non-small cell lung carcinoma.