Reid and colleagues showed that, in MPM, expression of miR-15a and miR-16 tumor suppressors inversely correlated to PDL1 expression and, similarly, low levels of miR-200 family members were found in PDL1-positive tumors; however they did not find differential expression of the three members of the miR-34 family in PDL1-positive and PD-L1-negative MPMs53,57. The gene discussed is CD274; the disease is neoplasm.