Using IHC staining, we found that compared to untreated controls, the AKI group had dramatically reduced cell proliferation in the kidney, as measured by the proliferation marker Ki67 (6.21 ± 2.26% vs. 2.01 ± 1.21% Ki67+, p < 0.05) (Fig. 5a). The gene discussed is MKI67; the disease is acute kidney injury.