The immunofluorescence (IF) staining of tumor tissues demonstrated that the miPEP133-overexpressing tumors had lower percentages of Ki67-positive proliferating cells, higher percentages of TUNEL positive apoptotic cells, and higher percentages of cleaved-caspase-3-positive apoptotic cells than the control tumors (Fig. 3f, g, h, and i). This evidence concerns the gene CASP3 and neoplasm.