The IKK enzyme complex is a part of the upstream NF-κB signal transduction cascade, so YHQ was evaluated for its effect on pIKKβ/NF-κB signaling molecules including NF-κB (p65), p-NF-κB (p65), IκBα, p-IκBα, IKKβ and p-IKKβ in pharyngeal mucous tissue of ammonia induced pharyngitis. Here, NFKBIA is linked to pharyngitis.