Our results revealed that the elevated expression level of RPS6KA1 was associated with the increased overall survival of lung cancer patients, when comparing the high level of gene expression (>median) to low level (<=median) (Hazard Ratio [HR] = 0.64, P = 5.9 × 10− 3) (Supplementary Table 8). Here, RPS6KA1 is linked to lung cancer.