NNT and cancer: Compared with adjacent noncancerous tissue and normal cell, upregulated NNT-AS1 expression was identified in most cancer tissues or cell lines and therefore indicated poor survival outcome, such as osteosarcoma [31], breast cancer [19], cervical cancer [30], gastric cancer [28], hepatocellular carcinoma [18], colorectal cancer [21], and non-small cell lung cancer (NSCLC) [2].