The results suggest that INHA was associated with significant lower OS and RFS rate compare with TIVA in several sub-variable groups indicating more severe liver cancer status, including tumor diameter ≥ 10 cm (Fig. 4b, d); AFP ≥ 400μg/L (Fig. 5b, d); PVTT typeIIand PVTT typeIII (Fig. 6c, e, f). The gene discussed is AFP; the disease is liver cancer.