LYPLA1 and papillary carcinoma: In the cBioPortal for Cancer Genomics database (TCGA), we selected a cohort of 507 samples of thyroid tumors, of which 77.3% correspond to papillary carcinomas, 20.7% follicular carcinomas, and 2% to poorly differentiated tumors [43], where we looked for genetic alterations in APT-1 (lysophospholipase 1, LYPLA1) and their association to those in HRAS and NRAS.