The neuropeptide VIPR1, finally, promotes bone mineralization [64,65,66,67,68], while TACR1 regulates the osteoblasts, osteoclasts and mesenchymal stem cell functionality associated with protection from osteoporosis [2,62,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85]. The gene discussed is VIPR1; the disease is osteoporosis.