SQSTM1 and neoplasm: Duan et al. reported that ellagic acid (10–50 μM) activated autophagy, but not apoptosis, in lung cancer cells (HOP62 and H1975), and in tumor-bearing mice (40 mg/kg, i.p., every 2 days, for 22 days), as demonstrated by the formation of LC3-positive autophagosomes, the increase in LC3 II, ATG5 and the reduced levels of p62 [238].