Yan et al. observed that baicalein (10, 20, 40 μM) induced the formation of autophagic vacuoles and increased the levels of LC3 II and Beclin 1, through the inhibition of the PI3K/Akt pathway, in MCF-7 and MDA-MB-231 breast cancer cells. The gene discussed is BECN1; the disease is breast carcinoma.