NOD1 and atherosclerosis: Moreover, a recent work combining Nod1 and Nod2 deficiency under the Ldlr−/− background shows similar results to those reported in this work [28]; however, in our animal model, whereas NOD1 was highly upregulated under HFD regime, NOD2 levels remained unchanged (Figure S9) stressing the relevance of NOD1 in the context of atherosclerosis.