Moreover, the expression of genes involved in the self-renewal and stem cell-maintenance signaling pathways, such as the Hedgehog, Notch and Wnt pathways, followed a differential pattern, whereby the Hedgehog and Notch signaling pathways were upregulated in the FUT9+ tumor cluster relative to the FUT9− tumor and the FUT9+ normal clusters. The gene discussed is FUT9; the disease is neoplasm.