LEP and polycystic ovary syndrome: Furthermore, in the PCOS group, we observed a positive association between the leptin/ghrelin ratio and total fat (r = 0.45, p < 0.01), SFA (r = 0.49, p < 0.01), MUFA (r = 0.45, p < 0.01), and PUFA (r = 0.34, p = 0.04) contained in the diet.