Further analysis of the correlations between BRD-containing protein genes and gene markers of different immune cells indicated that these 7 BRD genes were almost significantly associated with various gene markers of tumor-infiltrating immune cells, including PAX5, BCL6 and CD19 of B cells; CD8A, CTLA4 and LAT of CTLs; STAT4, TBX21 and CD4 of Th1 cells; GATA3, CXCR4 and CCR4 of Th2 cells; RORC, CCR6 and IL17A of Th17 cells; FOXP3, STAT5B and TGFB1 of Tregs; CCL2, IL10, CD163, VSIG4, CSF1R and FCGR2A of TAMs; ITGAX, CD1C and NRP1 of DCs; as well as CCR7, ITGAM and CD59 of neutrophils (Table 2). The gene discussed is CD4; the disease is neoplasm.