In the current study, we aimed to address this question through in-depth analysis of the expressions, mutations and predictive signaling pathways of 7 members from BRD gene family, namely BRD1, BRD2, BRD3, BRD4, BRD7, BRD8 and BRD9, and their associations with prognosis and immune infiltrates in HCC patients. Here, BRD8 is linked to hepatocellular carcinoma.