BCR and chronic myelogenous leukemia, BCR-ABL1 positive: CML is characterized by the presence of the Philadelphia chromosome (Ph), which contains a t(9;22)(q34;q11) reciprocal translocation that determines the formation of the chimeric Breakpoint Cluster Region-Abelson (BCR/ABL) gene, which encodes a 210-kDa oncoprotein [1].