We detected IL-6R expression in clinical ovarian cancer patient’s sample by IHC and found that IL-6R expression was much higher in ovarian cancer tissues (Figure 3A, p < 0.05), which might indicate that high levels of IL-6R would be required for PD-L1 induced via the miR-21/IL-6 feedback loop. The gene discussed is CD274; the disease is ovarian carcinoma.