CRP and Increased total leukocyte count: Laboratory studies revealed a worsening leukocytosis of 22.2 K/uL (Ref: 3.90–12.80 K/uL), an erythrocyte sedimentation rate (ESR) of >120 millimeters per hour (mm/hr) (Ref: 0–36 mm/hr), and a C-reactive protein (CRP) of 478.2 milligrams per liter (mg/L) (Ref: 0.0–8.2 mg/L).