Studies on homozygous Nfia−/− and heterozygous Nfia+/− mice have shown that lack of NFIA gene product is associated with the formation of hydrocephalus, the corpus callosum hypoplasia, and urinary tract defects (OMIM#613735) (Bayat, Kirchhoff, Madsen, Roos, & Kreiborg, 2017; Lu et al., 2007). Here, NFIA is linked to Hydrocephalus.