The high influence of similar driver genes on methylation patterns independent of location was also shown for atypical teratoid rhabdoid tumors (ATRTs) and non-central nervous system malignant rhabdoid tumors (extra-CNS MRTs) that are defined by SMARCB1 alterations and were mostly classified as AT/RT, MYC subgroup (85%) [26]. This evidence concerns the gene SMARCB1 and atypical teratoid rhabdoid tumor.