Urine biomarkers and their associations with AKI in patients with nephrotic syndrome: The urinary concentrations of KIM-1 and NGAL on renal biopsy had a good performance for indicating AKI based on the KDIGO criteria, with an area under the ROC curve of 0.8000 (95% CI = 0.6328-0.9672) and 0.8647 (95% CI= 0.7068-1.0000) respectively. The gene discussed is LCN2; the disease is acute kidney injury.