Interestingly, we found that BRCA tumor samples that belong to the basal subtype have higher expression of these three transcriptional regulators as well as a larger number of hypomethylated CENPA, FOXM1, and MYBL2-linked enhancers than other BRCA subtypes (i.e. luminal A, luminal B, Her2, normal-like) (Fig 6B). This evidence concerns the gene CENPA and neoplasm.