In order to identify mutation(s) that may have contributed to the development of DCM in the affected family members, we conducted whole exome sequencing in patient III-6 and identified four recessive variants within the linkage interval on chromosome 2: C2orf24, DNPEP, DOCK10, and SPEG (Table 3). The gene discussed is DOCK10; the disease is familial dilated cardiomyopathy.