NRG1 and infection: Infection of the 3 combinatorial RNL mutants with another obligate biotrophic oomycete pathogen, Albugo candida race 2V (Ac2V), which is recognized by the TNL WHITE RUST RESISTANCE 4A (WRR4A) and an unknown recessive disease resistance gene in Col-0 [13,32,33], demonstrated that NRG1 and ADR1 families can be fully redundant (Fig 1C).