TMEM79 and spina bifida: Injection of Tmem79 mRNA dorsally caused, in over 50% of embryos, an enlarged head indistinguishable from that caused by overexpression of other Wnt antagonists (Glinka et al., 1998; Zhang et al., 2012); Additionally, spina bifida was observed in another 30% embryos subjected with Tmem79 mRNA dorsal injection (Figure 6—figure supplement 1B), hinting at possible roles of Tmem79 in both AP patterning and morphogenesis.