Another study indicated that high D-dimer levels at initial presentation were predictive of coagulation-associated complications during hospitalization (D-dimer >2500 ng/mL, adjusted odds ratio - OR for thrombosis 6.79, for bleeding 3.56), critical illness, and death.53 Additional markers at initial presentation predictive of in-hospital thrombosis included platelet count >450 × 109/L (adjusted OR, 3.56), C-reactive protein (CRP) >100 mg/L (adjusted OR, 2.71), and erythrocyte sedimentation rate (ESR) >40 mm/h (adjusted OR, 2.64). The gene discussed is CRP; the disease is Venous thrombosis.