P0701 had a stop‐gain mutation and a missense mutation in FBXW7. P1012 had a missense mutation in NOTCH1. P0215 had a stop‐gain mutation in FBXW7. P0123 had a missense mutation in both NOTCH2 and FBXW7. P0909 had a frameshift deletion mutation in FBXW7 and a missense mutation in NOTCH1. T‐SNE analysis identified eight clusters (0‐7) of CD8+ T cells in tumour, adjacent normal mucosa and peripheral blood. Here, NOTCH2 is linked to neoplasm.