In order to discover whether the tumor suppressor properties of Samsn1 were also apparent in human myeloma cells, a combination of CRISPR‐Cas9 mutation and viral transgenesis was used to generate 4 different human myeloma cell lines (HMCLs) with matched SAMSN1‐high and SAMSN1‐low/null expression (Supplementary Figure S1). The gene discussed is SAMSN1; the disease is plasma cell myeloma.