Because of a T-ALL immature phenotype9,10 and a myeloid interface, and despite CD5 expression, this patient was diagnosed with near-ETP ALL.11 Molecular cytogenetic studies showed the presence of DDX3X-MLLT10 fusion gene derived from a three-way t(X;3;10)(p11;?;p13) translocation. This evidence concerns the gene CD5 and acute lymphoblastic leukemia.