TLR7 and systemic lupus erythematosus: Interestingly, the G allele of rs3853839 in the 3’ UTR of TLR7 has diminished binding capability to miR-3148, which was associated with elevated TLR7 transcript expression and increased risk for SLE, thus implicating miR-3148-TLR7 circuit in SLE pathogenesis40.