HOXC8 and central nervous system cancer: Moreover, in Fig. 1e and f, in CGGA array set, progression-free survival time of was shorter in higher HOXC8 expression group (p < 0.05). To further validation our results, we performed a univariate Cox regression analysis, the results showed that HOXC8 was showed a risk factor for glioma patients (p < 0.0001, HR = 1.545, Table 1).