These results showed that increased CA4 expression correlated with better prognosis and CA4 expression levels significantly correlated with B cell infiltration within KIRC, B cell, CD4+ T cell, macrophage, neutrophil and dendritic cell infiltration within LGG, B cell infiltration in PRAD, CD8+ T cell, CD4+ T cell and neutrophil infiltration within UVM (|partial.cor| > 0.2 and p<0.05). This evidence concerns the gene CD4 and prostate adenocarcinoma.