Based on Spearman’s rho, there was no significant difference in the mean IgE levels between gender (cases and controls) and presence of allergic diseases in cases, although, the highest mean was obtained from male allergic subjects (284.58 IU/mL) and those with AA (344.82 IU/mL) and AD (324.89 IU/mL). Here, IGHE is linked to Alzheimer disease.