SQSTM1 and neoplasm: As PCBP1 expression is shown to be broadly reduced in many types of tumor (Guo and Jia, 2018), our results here further demonstrate that PCBP1 represses intrinsic autophagic levels in both ovary tumors and colon tumors, indicating that p62 would be an general accompanying marker for other types of PCBP1-depleted tumors.