PCBP1 and neoplasm: Following this information, we then disclosed that PCBP1, as the suppressor of PRL-3, can really inhibit the starvation-induced autophagy of tumor cells to block tumorigenic initiation, independent of PRL-3 (Zhang et al., 2016), but we still do not know whether PCBP1 participates in the normal basal autophagy process in the nutrition-efficient situation.