Since same infection patterns could be displayed in THP1-DCs, moDCs and BDCA1+ DCs (9), we continued the next steps using WT THP1-DCs and their CD11b- and CD11c KO THP1-DCs counterparts to characterize in detail the specific roles of CR3 and CR4 during HIV-1 infection. This evidence concerns the gene CD1C and HIV-1 infection.