Although the CD47-SIRPα pathway is critical in controlling phagocytic function of monocytes/macrophages (41) we found that only 10% of the effector THP1 cells used in the assay expressed a low level of SIRP1α, excluding the involvement of this pathway in the different responses between MM and DLBCL cells to isatuximab-mediated ADCP. This evidence concerns the gene CD47 and diffuse large B-cell lymphoma.