Hepatic fibrosis induced by S. mansoni is not affected by the lack of TSLP, IL-25, and IL-33 signaling individually, but disruption of signaling by all three mediators reduced hepatic fibrosis, eosinophils, and innate lymphoid cell (ILC)-2 in the liver of mice (Vannella et al., 2016). The gene discussed is TSLP; the disease is Hepatic fibrosis.