SLC2A4 and type 2 diabetes mellitus: In the T2DM-SED mice, phosphorylation of GS at Ser640 (0.56-fold, p < 0.05) (Figures 7A,C) and the protein expression of GLUT4 (0.43-fold, p < 0.05) (Figures 7B,D) significantly decreased compared with those of CON mice.