FABP1 and Hyperglycemia: Previous animal studies of kidney disease have reported an upregulated expression of the human FABP1 gene in the kidneys, and that stress can cause increases in the urinary excretion of human FABP1 (e.g., urinary protein overload 4, tubular stretch 5, tubular ischemia 6, toxins 7, hyperglycemia 8, and hypertension 9).