Specifically, the expression levels of these 4 genes were increased > 4.0-fold in patients with sepsis compared with those in healthy subjects: ANXA3 (28.1-fold), S100A8 (4.9-fold), S100A9 (4.4-fold), and MMP9 (69.2-fold) (Figure 4B). Here, MMP9 is linked to Sepsis.