The presence of tumour-infiltrating lymphocytes, especially CD8+ cytotoxic T cells, is correlated with better prognosis of various cancers.32,33 To assess possible involvement of cytotoxic T cells in an antitumour response by host mice, we injected two isogenic cell lines, B16-Luc and LL/2-Luc, into naïve C57BL/6 mice and also into C57BL/6 mice that recovered from brain B16-Luc tumours following IF7C(RR)-SN38 treatment. Here, CD8A is linked to neoplasm.