Though there was no significant difference in FSH levels among all four groups, administration of troxerutin to rats for 4 weeks significantly reversed the elevated serum LH (300 mg/kg; P < 0.01) and testosterone levels (both 150 mg/kg and 300 mg/kg; P < 0.05), suggesting that troxerutin has a beneficial effect on the aberrant gonadotrophin and testosterone in PCOS rats. Here, BRD2 is linked to polycystic ovary syndrome.