CST1 was found to have different effect on survival in three individual cancer types with elevated express of CST1 associated with higher survival probability in BLCA and BRCA (the higher the expression of CST1, the higher the overall survival time of the patients), while reduced expression of CST1 associated with higher survival probability in LGG (the lower the expression of CST1, the higher the overall survival of the patients) (Figs S1D, S1E, and S1F). Here, CST1 is linked to bladder transitional cell carcinoma.