INS and Anorexia: Furthermore, the weighted median model supported the putative protective effect of elevated fasting insulin on risk for anorexia derived from the IVW (ORWeighted Median = 0.40, [95% CI:0.21–0.77], P = 6.3 × 10−3), as did the weighted mode estimator (ORWeighted Mode = 0.32 [95% CI: 0.13–0.84], P = 0.037).