Based on menopausal status combined with the depth of myometrial invasion of endometrial cancer, it was found that the expression of PGC-1α was related to the depth of myometrial invasion of premenopausal endometrial cancer (P = 0.022), but not to that of postmenopausal endometrial cancer (P = 0.056) (Table 4). The gene discussed is PPARGC1A; the disease is endometrial cancer.